" /> 【特集】免疫・アレルギー疾患における分子標的薬の使い方■血管炎症候群における分子標的薬の使い方■佐藤洋志,ほか |
呼吸臨床

【特集】免疫・アレルギー疾患における分子標的薬の使い方

企画:宮崎泰成


 近年,肺癌治療だけでなく,喘息を含む免疫アレルギー性疾患に分子標的薬が使用されるようになってきている。分子標的薬はそれぞれの免疫アレルギー性疾患の病態に直接ピンポイントに効果が期待できる。しかし,高価な薬でもあるので,有効性のエビデンス,どのような症例に,どのようなタイミングで使うのかなど新しい知識を身につけることが必要である。そこで「免疫・アレルギー疾患における分子標的薬の使い方」の特集を組んだ。

血管炎症候群における分子標的薬の使い方

佐藤洋志*,南木敏宏*

*東邦大学医学部内科学講座膠原病学分野(〒143-8541 東京都大田区大森西6-11-1)


Molecularly targeted drugs in vasculitis syndrome

Hiroshi Sato*,Toshihiro Nanki*

*Division of Rheumatology, Department of Internal Medicine, Toho University School of Medicine, Tokyo


Keywords:ANCA関連血管炎,Behçet病,高安動脈炎,巨細胞性動脈炎,分子標的薬/ANCA-associated vasculitis, Behcet’s disease, Takayasu arteritis, giant cell arteritis, molecularly targeted drugs


呼吸臨床 2019年3巻11号 論文No.e00074
Jpn Open J Respir Med 2019 Vol. 3 No. 11  Article No.e00074

DOI: 10.24557/kokyurinsho.3.e00074


掲載日:2019年11月8日


©️Hiroshi Sato, et al. 本論文の複製権,翻訳権,上映権,譲渡権,貸与権,公衆送信権(送信可能化権を含む)は弊社に帰属し,それらの利用ならびに許諾等の管理は弊社が行います。





要旨

 血管炎症候群は全身の血管に炎症を来す疾患である。各疾患は罹患血管径により分類されており,大型,中型,小型血管炎それぞれにおいて特有の肺病変を呈する。治療は副腎皮質ステロイドと免疫抑制薬が中心であるが,現在,分子標的薬も適応となっており効果が期待されている。今回,ANCA関連血管炎,Behçet病,高安動脈炎,巨細胞性動脈炎における分子標的薬の使い方について概説する。



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